HOOPER ~ mtDNA ~ PROJECT 


Mitochondrial DNA Concordance
by  K. W. P. Miller & J. L. Dawson

Cambridge Reference Sequences


Below is the mtDNA Migrations Map ~ Courtesy of Family Tree DNA:


The Seven European Daughters of Eve Matriarchal Groups
were given their names by Prof. Bryan Sykes:

1) Helena: This clan lived in the ice-capped Pyrenees. As the climate warmed, Helena’s descendants trekked northward to what is now England, some 12,000 years ago. Members of this group are now present in all European countries.

2) Jasmine: Her people had a relatively happy life in Syria, where they farmed wheat and raised domestic animals. Jasmine’s descendants traveled throughout Europe, spreading their agricultural innovations with them.

3) Katrine: Members of this group lived in Venice 10,000 years ago. Today most of Katrine’s clan lives in the Alps.

4) Tara: Sykes’ maternal ancestry goes back to this group, which settled in Tuscany 17,000 years ago. Descendants ventured across northern Europe and eventually crossed the English Channel.

5) Ursula: Users of stone tools, Ursula’s clan members drifted across all of Europe.

6) Valda: Originally from Spain, Valda and her immediate descendants lived 17,000 years ago. Later relatives moved into northern Finland and Norway.

7) Xenia: Her people lived in the Caucasus Mountains 25,000 years ago. Just before the Ice Age, this clan spread across Europe, and even reached the Americas. [As Dr. Wallace discovered, the X pattern is a rare European lineage and is also among the Northern Native Americans such as the Ojibwa and Sioux.]

Haplogroup:
% of Europeans:
Years Before Present:
Origin:
H = Helena
47
20,000
Southern France
J = Jasmine
17
10,000
Middle East
K = Katrine
6
15,000
Northern Italy
T = Tara
9
17,000
Tuscany
U = Ursula
11
45,000
Greece
V = Valda
5
17,000
Northern Spain
X = Xenia
6
25,000
Georgia - Asia
I = Ina (new - 8th)
<2
26,000
Unknown


Hooper mtDNA Participant Chart:

Each participant will have their own individual chart matching the one below but with
their own results supplied in the section denoting that individual participants results
in the yellow section.  For two individuals to compare their results, both claiming
the same female line ancestor, there must be an exact match in all differences
from the CRS standard.  If there are differences that don't match each
other, then there is not a genetic match between the two.


CRS Letter Reference:
Base Pairs
A
Adenine
C
Cytosine
G
Guanine
T
Thymine

~ HVR ~
The lab doesn't sequence the entire molecule, just the two "regions" where most changes (mutations) occur:

HVR1 - Hyper Variable Region 1 (CRS numbers 16001 - 16540) - Low Resolution and
HVR2 - Hyper Variable Region 2 (CRS numbers 00061 - 00570) - High Resolution

To see the Cambridge Reference Sequencing of the entire Mitochondrial DNA molecule,
go to the CRS link on this page (above). On that page, you'll see that the two
Hyper Variable Regions are highlighted.


In the Mitochondrial DNA Results Table below, it is important to note that each group is clumped in sets of 10 letters.  
Each of those letters refer to one of the Base Pairs listed above in the CRS Letter Reference.  Looking at the box titled
"16010", you should see "attctaattt".  To understand the numbering, realize that the number at the top is referencing
the very last letter (or base) in that particular group of 10.  So, the actual base that is number 16010 is "t".  The first one
in that group is an "a" and the corresponding number is 16001.  So the first group of 10 bases are numbers 16001 through
16010.  When a participant gets their results back, say for example, they may have a mutation at number 16009.  Say that
mutation is a "c", then the results would say: HVR1 16009C.  On the participants reuslts page, I will then change their own
chart to reflect the "t" at that spot to now a "C" and color it blue.  That way, you'll be able to see at a glance where the
mutations occur.


Mitochondrial DNA Results for Kit Number:
~ HVR1 ~
(Low Resolution Haplogroup and Mutations)
Cambridge Reference Sequence (CRS) in Small Letters.  Participant's Sequence in Capitols.
16010
16020
16030
16040
16050
16060
16070
16080
16090
16100
attctaattt
aaactattct
ctgttctttc
atggggaagc
agatttgggt
accacccaag
tattgactca
cccatcaaca
accgctatgt
atttcgtaca










16110
16120
16130
16140
16150
16160
16170
16180
16190
16200
ttactgccag
ccaccatgaa
tattgtacgg
taccataaat
acttgaccac
ctgtagtaca
taaaaaccca
atccacatca
aaaccccctc
cccatgctta










16210
16220
16230
16240
16250
16260
16270
16280
16290
16300
caagcaagta
cagcaatcaa
ccctcaacta
tcacacatca
actgcaactc
caaagccacc
cctcacccac
taggatacca
acaaacctac
ccacccttaa










16310
16320
16330
16340
16350
16360
16370
16380
16390
16400
cagtacatag
tacataaagc
catttaccgt
acatagcaca
ttacagtcaa
atcccttctc
gtccccatgg
atgacccccc
tcagataggg
gtcccttgac










16410
16420
16430
16440
16450
16460
16470
16480
16490
16500
caccatcctc
cgtgaaatca
atatcccgca
caagagtgct
actctcctcg
ctccgggccc
ataacacttg
ggggtagcta
aagtgaactg
tatccgacat










16510
16520
16530
16540












ctggttccta
cttcagggtc
ataaagccta
aatagcccac




~ HVR2 ~
(High Resolution Haplogroup and Mutations)
Cambridge Reference Sequence (CRS) in Small Letters.  Participant's Sequence in Capitols.
00070
00080
00090
00100
00110
00120
00130
00140
00150
00160
cgtctggggg
gtatgcacgc
gatagcattg
cgagacgctg
gagccggagc
accctatgtc
gcagtatctg
tctttgattc
ctgcctcatc
ctattattta










00170
00180
00190
00200
00210
00220
00230
00240
00250
00260
tcgcacctac
gttcaatatt
acaggcgaac
atacttacta
aagtgtgtta
attaattaat
gcttgtagga
cataataata
acaattgaat
gtctgcacag










00270
00280
00290
00300
00310
00320
00330
00340
00350
00360
ccactttcca
cacagacatc
ataacaaaaa
atttccacca
aaccccccct
cccccgcttc
tggccacagc
acttaaacac
atctctgcca
aaccccaaaa










00370
00380
00390
00400
00410
00420
00430
00440
00450
00460
acaaagaacc
ctaacaccag
cctaaccaga
tttcaaattt
tatcttttgg
cggtatgcac
ttttaacagt
caccccccaa
ctaacacatt
attttcccct










00470
00480
00490
00500
00510
00520
00530
00540
00550
00560
cccactccca
tactactaat
ctcatcaata
caacccccgc
ccatcctacc
cagcacacac
acaccgctgc
taaccccata
ccccgaacca
accaaacccc










00570



























aaagacaccc

~ Participant Results Summary ~
Haplogroup:
Age (Years Ago):
% of Europeans
Origin:






Mitochondrial DNA Participants:

Participant # 3783
Participant # 5146

Participant # 7010
Participant # 884

Participant # 7278
Participant # 7328
Participant # 7420
Participant # 8338

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